772 research outputs found

    Event Reconstruction with MarlinReco at the ILC

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    After an overview of the modular analysis and reconstruction framework Marlin an introduction on the functionality of the Marlin-based reconstruction package MarlinReco is given. This package includes a full set of modules for event reconstruction based on the Particle Flow approach. The status of the software is reviewed and recent results using this software package for event reconstruction are presented.Comment: 6 pages, 2 .eps figures, to appear in Proc. LCWS06, Bangalore, March 200

    Poor sleep in multiple sclerosis correlates with Beck Depression Inventory values, but not with polysomnographic data

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    Objectives. Pittsburgh Sleep Quality Index (PSQI) values correlate with depression, but studies investigating the relationship between PSQI values and polysomnographic (PSG) data showed inconsistent findings. Methods. Sixty-five consecutive patients with multiple sclerosis (MS) were retrospectively classified as "good sleepers" (GS) (PSQI ≀ 5) and "poor sleepers" (PS) (PSQI > 5). The PSG data and the values of the Visual Analog Scale (VAS) of fatigue, Modified Fatigue Impact Scale (MFIS), Fatigue Severity Scale (FSS), Epworth Sleepiness Scale (ESS), and the Beck Depression Inventory (BDI) were compared. Results. No significant differences were found either for PSG data or for ESS, MFIS, and FSS values; but PS showed significantly increased BDI and VAS values. Conclusions. Poor sleep is associated with increased depression and fatigue scale values

    Monolithic Pixel Sensors in Deep-Submicron SOI Technology

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    Monolithic pixel sensors for charged particle detection and imaging applications have been designed and fabricated using commercially available, deep-submicron Silicon-On-Insulator (SOI) processes, which insulate a thin layer of integrated full CMOS electronics from a high-resistivity substrate by means of a buried oxide. The substrate is contacted from the electronics layer through vias etched in the buried oxide, allowing pixel implanting and reverse biasing. This paper summarizes the performances achieved with a first prototype manufactured in the OKI 0.15 micrometer FD-SOI process, featuring analog and digital pixels on a 10 micrometer pitch. The design and preliminary results on the analog section of a second prototype manufactured in the OKI 0.20 micrometer FD-SOI process are briefly discussed.Comment: Proceedings of the PIXEL 2008 International Workshop, FNAL, Batavia, IL, 23-26 September 2008. Submitted to JINST - Journal of Instrumentatio

    Sleep disorders reduce health-related quality of life in multiple sclerosis (Nottingham Health Profile data in patients with multiple sclerosis)

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    Quality of Life (QoL) is decreased in multiple sclerosis (MS), but studies about the impact of sleep disorders (SD) on health-related quality of Life (HRQoL) are lacking. From our original cohort, a cross-sectional polysomnographic (PSG) study in consecutive MS patients, we retrospectively analysed the previously unpublished data of the Nottingham Health Profile (NHP). Those MS patients suffering from sleep disorders (n = 49) showed significantly lower HRQoL compared to MS patients without sleep disorders (n = 17). Subsequently, we classified the patients into four subgroups: insomnia (n = 17), restless-legs syndrome, periodic limb movement disorder and SD due to leg pain (n = 24), obstructive sleep apnea (n = 8) and patients without sleep disorder (n = 17). OSA and insomnia patients showed significantly higher NHP values and decreased HRQoL not only for the sleep subscale but also for the "energy" and "emotional" area of the NHP. In addition, OSA patients also showed increased NHP values in the "physical abilities" area. Interestingly, we did not find a correlation between the objective PSG parameters and the subjective sleep items of the NHP. However, this study demonstrates that sleep disorders can reduce HRQoL in MS patients and should be considered as an important confounder in all studies investigating HRQoL in MS

    Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity

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    Background: There are few studies describing periodic limb movement syndrome (PLMS) in rapid eye movement (REM) sleep in patients with narcolepsy, restless legs syndrome, REM sleep behavior disorder, and spinal cord injury, and to a lesser extent, in insomnia patients and healthy controls, but no published cases in multiple sclerosis (MS). The aim of this study was to investigate PLMS in REM sleep in MS and to analyze whether it is associated with age, sex, disability, and laboratory findings. Methods: From a study of MS patients originally published in 2011, we retrospectively analyzed periodic limb movements (PLMs) during REM sleep by classifying patients into two subgroups: PLM during REM sleep greater than or equal to ten per hour of REM sleep (n=7) vs less than ten per hour of REM sleep (n=59). A univariate analysis between PLM and disability, age, sex, laboratory findings, and polysomnographic data was performed. Results: MS patients with more than ten PLMs per hour of REM sleep showed a significantly higher disability measured by the Kurtzke expanded disability status scale (EDSS) (P=0.023). The presence of more than ten PLMs per hour of REM sleep was associated with a greater likelihood of disability (odds ratio 22.1; 95% confidence interval 3.5–139.7; P<0.0001), whereas there were no differences in laboratory and other polysomnographic findings. Conclusion: PLMs during REM sleep were not described in MS earlier, and they are associated with disability measured by the EDSS

    A Study of e+e- -> H0A0 Production and the Constraint on Dark Matter Density

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    This paper reports the results of a study of the e+e- -> H0A0 process at 1 TeV performed on fully simulated and reconstructed events. The estimated accuracies on the heavy Higgs boson masses, widths and decay branching fractions are discussed in relation to the study of Supersymmetric Dark Matter.Comment: 5 pages, 4 figures, submitted to Phys. Rev.

    Theoretical study of dark resonances in micro-metric thin cells

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    We investigate theoretically dark resonance spectroscopy for a dilute atomic vapor confined in a thin (micro-metric) cell. We identify the physical parameters characterizing the spectra and study their influence. We focus on a Hanle-type situation, with an optical irradiation under normal incidence and resonant with the atomic transition. The dark resonance spectrum is predicted to combine broad wings with a sharp maximum at line-center, that can be singled out when detecting a derivative of the dark resonance spectrum. This narrow signal derivative, shown to broaden only sub-linearly with the cell length, is a signature of the contribution of atoms slow enough to fly between the cell windows in a time as long as the characteristic ground state optical pumping time. We suggest that this dark resonance spectroscopy in micro-metric thin cells could be a suitable tool for probing the effective velocity distribution in the thin cell arising from the atomic desorption processes, and notably to identify the limiting factors affecting desorption under a grazing incidence.Comment: 12 pages, 11 figures theoretical articl

    Les temps de la consultation du comitĂ© d’entreprise

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    The DD4HEP detector description toolkit offers a flexible and easy-to-use solution for the consistent and complete description of particle physics detectors in a single system. The sub-component DDREC provides a dedicated interface to the detector geometry as needed for event reconstruction. With DDREC there is no need to define an additional, separate reconstruction geometry as is often done in HEP, but one can transparently extend the existing detailed simulation model to be also used for the reconstruction. Based on the extension mechanism of DD4HEP, DDREC allows one to attach user defined data structures to detector elements at all levels of the geometry hierarchy. These data structures define a high level view onto the detectors describing their physical properties, such as measurement layers, point resolutions, and cell sizes. For the purpose of charged particle track reconstruction, dedicated surface objects can be attached to every volume in the detector geometry. These surfaces provide the measurement directions, local-to-global coordinate transformations, and material properties. The material properties, essential for the correct treatment of multiple scattering and energy loss effects in charged particle reconstruction, are automatically averaged from the detailed geometry model along the normal of the surface. Additionally, a generic interface allows the user to query material properties at any given point or between any two points in the detector's world volume. In this paper we will present DDREC and how it is used together with the linear collider tracking software and the particle-flow package PANDORAPFA for full event reconstruction of the ILC detector concepts ILD and SiD, and of CLICdp. This flexible tool chain is also well suited for other future accelerator projects such as FCC and CEPC

    Calomplification — the power of generative calorimeter models

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    Motivated by the high computational costs of classical simulations, machine-learned generative models can be extremely useful in particle physics and elsewhere. They become especially attractive when surrogate models can efficiently learn the underlying distribution, such that a generated sample outperforms a training sample of limited size. This kind of GANplification has been observed for simple Gaussian models. We show the same effect for a physics simulation, specifically photon showers in an electromagnetic calorimeter

    Forward tracking at the next \boldmath{e+e−e^+e^-} collider Part II: experimental challenges and detector design

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    We present the second in a series of studies into the forward tracking system for a future linear e+e− e^+ e^- collider with a center-of-mass energy in the range from 250 GeV to 3 TeV. In this note a number of specific challenges are investigated, that have caused a degradation of the tracking and vertexing performance in the forward region in previous experiments. We perform a quantitative analysis of the dependence of the tracking performance on detector design parameters and identify several ways to mitigate the performance loss for charged particles emitted at shallow angle
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